Meeting Archive:
CHT Column Packing is Easier Than You Think


Meeting Description:
Please join us to learn best practices and guidelines for packing CHTTM Ceramic Hydroxyapatite Media at process scale. CHT, is an easy-to-use mixed-mode chromatography media. It offers cation exchange and affinity interactions. Unlike other chromatography media, CHT is both the ligand and the support matrix. It is used for the purification of numerous types of biomolecules and is considered the gold standard for aggregate removal.

This webinar will highlight CHT Media transfer methodologies and column packing guidelines. CHT is incompressible and has high specific gravity, a rapid settling rate, and sensitivity to mechanical shear. These variations from traditional compressible resins have to be considered when designing CHT column-packing protocols. In this webinar our expert, Dr. Mark Snyder, will provide recommendations and guidelines for successful CHT column packing.

You will learn:
  • Slurry preparation techniques
  • Slurry transfer methodologies
  • Column packing guidelines
  • Packed column evaluation and qualification testing
  • Post-packing considerations
Details
Date: Wed, Sep 6, 2017
Time: 11:00 AM EDT
Duration: 15 minutes
Host(s): BioProcess International
 Presenter Information
Dr. Mark Snyder
Speaker Photo

Dr. Mark A. Snyder is Manager of the Process R&D Applications Group in the Process Chromatography Division of Bio-Rad Laboratories. He received a BS degree from the Massachusetts Institute of Technology and his PhD in Biochemistry from the University of California, Berkeley. He has been responsible for many developed processes, including Bayer’s current-generation licensed recombinant Factor VIII purification process. He is experienced in process troubleshooting, optimization, and validation. His work has been published in numerous peer-reviewed journals.