Meeting Archive:
ASPHO Live Webinar: Impact of Obesity on Outcomes in Childhood ALL Survivors

Meeting Description:

Childhood acute lymphoblastic leukemia (ALL) is the most common childhood cancer, accounting for almost one-quarter of childhood cancer survivors. Survivors of childhood ALL are at increased risk of obesity and have a higher incidence of diabetes mellitus, metabolic syndrome and cardiovascular disease than their peers.  Causes of this increased risk are multifactorial and include treatment with corticosteroids and decreased physical activity both during treatment and following therapy.  

We will look at mechanisms related to ALL treatment that increase risk factors during treatment and subsequently leading to long-term risk of Cardiovascular disease, obesity and insulin resistance. We will discuss interventions that can alter the metabolic pathways to cardiometabolic disease.

Learning Objectives:

  • Describe the multifactorial physiologic mechanisms for obesity and cardiometabolic disease and discuss potential prevention strategies for pediatric ALL patients.
  • Discuss the impact of obesity on childhood ALL survivors and long-term health-related outcomes into adult years.
Date: Wed, Nov 15, 2017
Time: 03:00 PM CST
Duration: 1 hour
Host(s): The American Society of Pediatric Hematology/Oncology
 Presenter Information
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Mukta Sharma, MD, MPH, Associate Professor, University of Missouri, Kansas City, Children’s Mercy Division of Pediatric Hematology Oncology

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Jill Hickman Simmons, MD. Associate Professor of Pediatrics, Ian Burr Division of Pediatric Endocrinology and Diabetes, Vanderbilt University School of Medicine. 

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Emily S. Tonorezos, MD, MPH. Clinical Director, Adult Long-Term Follow-Up Program at Memorial Sloan Kettering Cancer Center.