Meeting Archive:
Single-Use Technology and Sustainability: Quantifying the Environmental Impact


Meeting Description:

Biopharmaceutical development and manufacturing require scalable processes that can be quickly developed, easily implemented, and smoothly transferred to production. The use of single-use technologies within the biopharmaceutical industry continues to increase as these technologies provide important flexibility for bioprocessing. Meanwhile the world continues to face mounting pressure related to a variety of environmental concerns including climate, water scarcity, and other resource availability issues. Rapid shifts in technology or technology adoption present an opportunity, and an obligation, to evaluate sustainability implications.

This webinar presents comparative studies of the environmental impacts of producing monoclonal antibodies using either single-use or traditional process technology. The studies are based on Life cycle assessment (LCA) methodology. LCA considers environmental impacts across the entire life cycle of each process component, from material extraction and refining through component manufacturing, packaging, distribution, use, and disposal at end-of-life.

The results from the first  study indicate that the single-use process train exhibits lower environmental impacts compared to the traditional process train, primarily due to a reduced need for large amounts of energy-intensive water-for-injection, process water, and clean steam. In the second study a more detailed investigation is done, with multiple unit operations included.  A variety of end-of-life treatment options for single-use components is assessed. Implementation of single-use process technology in existing facilities as well as in standalone turnkey facilities in multiple global regions will be discussed.

Details
Date: Wed, Jun 1, 2016
Time: 11:00 AM EDT
Duration: 30 minutes
Host(s): BioProcess International
 Presenter Information
Dr. Bill Flanagan
Speaker Photo

Bill Flanagan leads the Ecoassessment Center of Excellence for GE. The team works with the various GE businesses and the GE Ecomagination leadership team to support the company’s product and technology sustainability strategies, applying a variety of tools and approaches including environmental life cycle assessment. Dr. Flanagan is Chair, Board of Directors, of the American Center for Life Cycle Assessment (ACLCA), the membership and advocacy organization for LCA professionals in North America, and also serves on the External Advisory Board for the University of Michigan’s Center for Sustainable Systems. He holds a PhD in Chemical Engineering from the University of Connecticut, USA.